The effects of maternal diabetes on expression of insulin-like growth factor-1 and insulin receptors in male developing rat hippocampus

@article{Hami2011TheEO,
  title={The effects of maternal diabetes on expression of insulin-like growth factor-1 and insulin receptors in male developing rat hippocampus},
  author={Javad Hami and Ariane Sadr-Nabavi and Mojtaba Sankian and Mehdi Balali-Mood and Hossein Haghir},
  journal={Brain Structure and Function},
  year={2011},
  volume={218},
  pages={73-84}
}
Diabetes during pregnancy causes neurodevelopmental and neurocognitive abnormalities in offspring. Insulin and insulin-like growth factor-1 (IGF-1) are important regulators of developmental and cognitive functions in the central nervous system. We examined the effects of maternal diabetes on insulin-like growth factor-1 receptor (IGF-1R) and insulin receptor (InsR) expression in the developing rat hippocampus. Female rats were maintained diabetic from a week before pregnancy through parturition… CONTINUE READING
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A review of maternal and fetal growth factors in diabetic pregnancy

  • M Higgins, F Mc Auliffe
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