The effects of maternal betamethasone administration on the intrauterine growth-restricted fetus.

@article{Miller2007TheEO,
  title={The effects of maternal betamethasone administration on the intrauterine growth-restricted fetus.},
  author={Suzanne L Miller and Mahalia Chai and Jan M Loose and Margie Castillo-Mel{\'e}ndez and David W Walker and Graham Jenkin and Euan M Wallace},
  journal={Endocrinology},
  year={2007},
  volume={148 3},
  pages={1288-95}
}
Intrauterine growth restriction (IUGR) is associated with altered fetal cardiovascular function to ensure adequate perfusion of essential organs. IUGR fetuses are at risk of preterm delivery and so are likely to receive antenatal glucocorticoids to promote lung maturation. Because glucocorticoids alter vascular tone, we questioned whether such treatment may induce fetal cardiovascular alterations. Using pregnant sheep carrying twins, we induced IUGR at approximately 0.7 gestation by single… CONTINUE READING

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