The effects of magnetite (Fe3O4) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH3) cells and in RAW 264.7 macrophages

@inproceedings{Liu2012TheEO,
  title={The effects of magnetite (Fe3O4) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH3) cells and in RAW 264.7 macrophages},
  author={Yen-Chin Liu and P Wu and Dar-Bin Shieh and Sheng-Nan Wu},
  booktitle={International journal of nanomedicine},
  year={2012}
}
AIMS Fe₃O₄ nanoparticles (NPs) have been known to provide a distinct image contrast effect for magnetic resonance imaging owing to their super paramagnetic properties on local magnetic fields. However, the possible effects of these NPs on membrane ion currents that concurrently induce local magnetic field perturbation remain unclear. METHODS We evaluated whether amine surface-modified Fe₃O₄ NPs have any effect on ion currents in pituitary tumor (GH₃) cells via voltage clamp methods. RESULTS… CONTINUE READING
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