The effects of levothyroxine replacement or suppressive therapy on health status, mood, and cognition.

@article{Samuels2014TheEO,
  title={The effects of levothyroxine replacement or suppressive therapy on health status, mood, and cognition.},
  author={Mary H. Samuels and Irina Kolobova and Anne Smeraglio and Dawn M. Peters and Jeri S. Janowsky and Kathryn G. Schuff},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2014},
  volume={99 3},
  pages={
          843-51
        }
}
CONTEXT TSH-suppressive doses of levothyroxine (L-T4) have adverse effects on bone and cardiac function, but it is unclear whether central nervous system function is also affected. OBJECTIVE The aim of the study was to determine whether women receiving TSH-suppressive L-T4 doses have decrements in health status, mood, or cognitive function. DESIGN AND SETTING A cross-sectional comparison was made among three groups of women in an academic medical center research clinic. PATIENTS Twenty… CONTINUE READING

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