Corpus ID: 22554981

The effects of leptin in combination with a cannabinoid receptor 1 antagonist, AM 251, or cannabidiol on food intake and body weight in rats fed a high-fat or a free-choice high sugar diet.

@article{WieruckaRybak2014TheEO,
  title={The effects of leptin in combination with a cannabinoid receptor 1 antagonist, AM 251, or cannabidiol on food intake and body weight in rats fed a high-fat or a free-choice high sugar diet.},
  author={M. Wierucka-Rybak and M. Wolak and E. Bojanowska},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2014},
  volume={65 4},
  pages={
          487-96
        }
}
  • M. Wierucka-Rybak, M. Wolak, E. Bojanowska
  • Published 2014
  • Chemistry, Medicine
  • Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
  • High intake of fats and sugars has prompted a rapid growth in the number of obese individuals worldwide. To further investigate whether simultaneous pharmacological intervention in the leptin and cannabinoid system might change food and water intake, preferences for palatable foods, and body weight, we have examined the effects of concomitant intraperitoneal administration of leptin and AM 251, a cannabinoid 1 (CB1) receptor antagonist, or cannabidiol (CBD), a plant cannabinoid, in rats… CONTINUE READING
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