The effects of lead on transient outward currents of acutely dissociated rat dorsal root ganglia

@article{Dai2001TheEO,
  title={The effects of lead on transient outward currents of acutely dissociated rat dorsal root ganglia},
  author={X Dai and Di-yun Ruan and Ju-tao Chen and M Wang and L Cai},
  journal={Brain Research},
  year={2001},
  volume={904},
  pages={327-340}
}
The effects of Pb2+ on transient outward currents (TOCs) were investigated on rat dorsal root ganglia (DRG) neurons at postnatal days of 15 approximately 21, using the conventional whole-cell patch-clamp technique. In media-sized (35 approximately 40 microm) neurons and in the presence of 50 mM TEA, TOCs that preliminarly included an A-current (IA) and a D-current (ID), were clearly present and dominant. Application of Pb2+ lengthened the initial delay of TOCs and increased the onset-peak time… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.

Similar Papers

Loading similar papers…