The effects of ladasten on dopaminergic neurotransmission and hippocampal synaptic plasticity in rats

@article{Mikhaylova2007TheEO,
  title={The effects of ladasten on dopaminergic neurotransmission and hippocampal synaptic plasticity in rats},
  author={Marina Mikhaylova and Julia V. Vakhitova and Renat S. Yamidanov and M. Kh. Salimgareeva and Sergey B. Seredenin and Thomas Behnisch},
  journal={Neuropharmacology},
  year={2007},
  volume={53},
  pages={601-608}
}
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MPTP-meditated hippocampal dopamine deprivation modulates synaptic transmission and activity-dependent synaptic plasticity.
Effects of the Novel Anti-Asthenic Drug Ladasten on Behavior and T-Cell Subsets Alterations in a Social Defeat Animal Model of Depression
TLDR
The notion that depression is accompanied by cell-mediated immune activation and that targeting this pathway may be a new therapeutic approach for treatment is supported and further investigations of ladasten as a potent anti-depressive drug which can be used alone as well as in combination with other anti-Depressants are supported.
Changes in CREB (SER133) Content and DNA-Binding Activity of Transcriptional Factors in Rat Brain Cells against the Background of Ladasten Exposure
We studied the effects of single administration of ladasten (50 mg/kg) on the level of transcriptional factor CREB (cyclic AMP response binding element protein) phosphorylated by Ser133 in rat…
MPTP modulates hippocampal synaptic transmission and activity‐dependent synaptic plasticity via dopamine receptors
J. Neurochem. (2012) 122, 582–593.
Two‐Step Synthesis of Heptacyclo[6.6.0.02,6.03,13.04,11.05,9.010,14] tetradecane from Norbornadiene: Mechanism of the Cage Assembly and Post‐synthetic Functionalization
Abstract A selective and scalable two‐step approach to the dimerization of norbornadiene (NBD) into its thermodynamically most stable dimer, heptacyclo[6.6.0.02,6.03,13.04,11.05,9.010,14]…
Towards an Effective Synthesis of Difunctionalized Heptacyclo [6.6.0.0 2,6 .0 3,13 .0 4,11 .0 5,9 .0 10,14 ]tetradecane: Ligand Effects on the Cage Assembly and Selective C−H Arylation Reactions
Two‐Step Synthesis of Heptacyclo[6.6.0.0 2,6 .0 3,13 .0 4,11 .0 5,9 .0 10,14 ] tetradecane from Norbornadiene: Mechanism of the Cage Assembly and Post‐synthetic Functionalization

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