The effects of lactoferrin on gram-negative bacteria.

  title={The effects of lactoferrin on gram-negative bacteria.},
  author={Richard T. Ellison},
  journal={Advances in experimental medicine and biology},
Lactoferrin is an iron-binding protein found in human mucosal secretions as well as the specific granules of polymorphonuclear leukocytes. A variety of functions have been ascribed to the protein, and it appears to contribute to antimicrobial host defense. In particular, it has been shown to have direct effects on pathogenic microorganisms including bacteriostasis and the induction of microbial iron uptake systems. Still its overall physiologic role remains to be defined. It has appeared… CONTINUE READING