The effects of lactate and beta-hydroxybutyrate on the energy metabolism and neural activity of hippocampal slices from adult and immature rat.

@article{Wada1997TheEO,
  title={The effects of lactate and beta-hydroxybutyrate on the energy metabolism and neural activity of hippocampal slices from adult and immature rat.},
  author={Hideo Wada and Yoshio Okada and M Nabetani and Hidenori Nakamura},
  journal={Brain research. Developmental brain research},
  year={1997},
  volume={101 1-2},
  pages={1-7}
}
We investigated the correlation between energy metabolism and neural activity during glucose deprivation and during replacement of glucose with lactate and beta-hydroxybutyrate (OHBA) in neural tissue from rats of different ages. Hippocampal slices were prepared from 4-, 7-, 10-, 13- and 16-day-old and adult rats. The population spikes (PS) were recorded in the pyramidal cell layer of the CA3 area as the index of neural activity. ATP and creatine-phosphate (CrP) levels in each slice were… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…