The effects of intravenous pulse methylprednisolone on immunological and inflammatory processes in ankylosing spondylitis.

@article{Richter1983TheEO,
  title={The effects of intravenous pulse methylprednisolone on immunological and inflammatory processes in ankylosing spondylitis.},
  author={Monika Richter and Patricia Woo and Gabriel S. Panayi and Andrew K. Trull and Arleen Unger and Philip Shepherd},
  journal={Clinical and experimental immunology},
  year={1983},
  volume={53 1},
  pages={51-9}
}
Acute phase reactants, serum immunoglobulins and immune complexes and T cell function were measured in eight patients with active ankylosing spondylitis (AS) before and up to 3 months after three pulses of 1 g methylprednisolone. There was a two stage effect. The first stage was an early anti-inflammatory event with a fall in clinical disease activity mirrored by changes in acute phase reactants particularly prealbumin. The second stage occurred later and was an immunological event with a fall… CONTINUE READING

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