The effects of intravenous doxycycline therapy for rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial.

Abstract

OBJECTIVE To determine the feasibility, safety, and potential clinical efficacy of intravenous (IV) doxycycline therapy for rheumatoid arthritis (RA), as well as its possible effects on serum and urinary markers of collagen breakdown. METHODS The exploratory trial was designed as a 16-week, single-center, randomized, double-blind, placebo-controlled trial… (More)

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