The effects of intra-cerebral drug infusions on animals' unconditioned fear reactions: a systematic review.

@article{Engin2008TheEO,
  title={The effects of intra-cerebral drug infusions on animals' unconditioned fear reactions: a systematic review.},
  author={Elif Engin and Dallas Treit},
  journal={Progress in neuro-psychopharmacology & biological psychiatry},
  year={2008},
  volume={32 6},
  pages={1399-419}
}
Intra-cerebral (i.c.) microinfusion of selective receptor agonists and antagonists into behaving animals can provide both neuroanatomical and neurochemical insights into the neural mechanisms of anxiety. However, there have been no systematic reviews of the results of this experimental approach that include both a range of unconditioned anxiety reactions and a sufficiently broad theoretical context. Here we focus on amino acid, monoamine, cholinergic and peptidergic receptor ligands… CONTINUE READING
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