The effects of innervation on the developmental expression of Ca(2+)-activated K+ currents in embryonic parasympathetic neurons are not activity-dependent.

@article{Subramony1996TheEO,
  title={The effects of innervation on the developmental expression of Ca(2+)-activated K+ currents in embryonic parasympathetic neurons are not activity-dependent.},
  author={Priya Subramony and Stuart E Dryer},
  journal={Brain research. Developmental brain research},
  year={1996},
  volume={91 1},
  pages={149-52}
}
Chronic blockade of synaptic transmission in ovo using mecamylamine, a neuronal nicotinic receptor antagonist, caused a large increase in naturally occurring cell death in the embryonic chick ciliary ganglion. However, the Ca(2+)-activated K+ currents in embryonic day 13 mecamylamine-treated ciliary ganglion neurons were indistinguishable from those of saline-treated controls. Therefore, the trophic effect of preganglionic innervation on the developmental expression of Ca(2+)-activated K… CONTINUE READING