The effects of inhaled budesonide on circulating eosinophil progenitors and their expression of cytokines after allergen challenge in subjects with atopic asthma.

@article{Gauvreau2000TheEO,
  title={The effects of inhaled budesonide on circulating eosinophil progenitors and their expression of cytokines after allergen challenge in subjects with atopic asthma.},
  author={Gail M Gauvreau and Lorna J Wood and Roma Sehmi and Rick M. Watson and Sandra C. Dorman and Robert P. Schleimer and Judah A. Denburg and Paul M O'Byrne},
  journal={American journal of respiratory and critical care medicine},
  year={2000},
  volume={162 6},
  pages={2139-44}
}
Allergen inhalation by dual responder subjects with atopic asthma is associated with an increase in circulating eosinophil/basophil colony-forming units (Eo/B CFU) and granulocyte-macrophage colony- stimulating factor (GM-CSF) immunolocalization in Eo/B colony cells grown in vitro. The current study examined the effect of the inhaled corticosteroid, budesonide, on the number of allergen- induced circulating eosinophils and Eo/B CFU, and immunolocalization of GM-CSF and interleukin-5 (IL-5) in… CONTINUE READING

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