The effects of ileal transposition on food intake and body weight loss in VMH-obese rats.

@article{Koopmans1982TheEO,
  title={The effects of ileal transposition on food intake and body weight loss in VMH-obese rats.},
  author={Henry S Koopmans and Anthony Sclafani and Christopher G. Fichtner and Paul F. Aravich},
  journal={The American journal of clinical nutrition},
  year={1982},
  volume={35 2},
  pages={284-93}
}
Rats were made obese by VMH knife-cuts and then a 5 or 10 cm segment of terminal ileum was transposed to the duodenum. After surgery, the food moved from the stomach into upper duodenum and then traveled through the transposed ileal segment to lower duodenum and continued down the remaining normal digestive tract. Ileal transposition caused a significant reduction in food intake and a substantial loss of body weight. There was no difference in weight loss with 5 and 10 cm ileal transpositions… CONTINUE READING
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