The effects of hyperoxia on microvascular endothelial cell proliferation and production of vaso-active substances

@inproceedings{Attaye2017TheEO,
  title={The effects of hyperoxia on microvascular endothelial cell proliferation and production of vaso-active substances},
  author={Ilias Attaye and Yvo Michiel Smulders and Gilles Ledoux and Heleen M Oudemans-van Straaten and Bob Smit and Michiel H. van Wijhe and Ren{\'e} J. P. Musters and Pieter Koolwijk and Ang{\'e}lique M E Spoelstra-de Man},
  booktitle={Intensive care medicine experimental},
  year={2017}
}
BACKGROUND Hyperoxia, an arterial oxygen pressure of more than 100 mmHg or 13% O2, frequently occurs in hospitalized patients due to administration of supplemental oxygen. Increasing evidence suggests that hyperoxia induces vasoconstriction in the systemic (micro)circulation, potentially affecting organ perfusion. This study addresses effects of hyperoxia on viability, proliferative capacity, and on pathways affecting vascular tone in cultured human microvascular endothelial cells (hMVEC… CONTINUE READING
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