The effects of hydrated C(60) fullerene on gene expression profile of TRPM2 and TRPM7 in hyperhomocysteinemic mice.

@article{Etem2014TheEO,
  title={The effects of hydrated C(60) fullerene on gene expression profile of TRPM2 and TRPM7 in hyperhomocysteinemic mice.},
  author={Ebru Onalan Etem and Ramazan Bal and Arzu Etem Akağaç and Tuncay Kuloğlu and Mehmet Tuzcu and Grigory V Andrievsky and Ilay Buran and Victor S. Nedzvetsky and Gıyasettin Baydaş},
  journal={Journal of receptor and signal transduction research},
  year={2014},
  volume={34 4},
  pages={317-24}
}
BACKGROUND Hyperhomocysteinemia (HHcy) is associated with neurodegenerative diseases. Transient receptor potential melastatin (TRPM2) and TRPM7 channels may be activated by oxidative stress. Hydrated C(60) fullerene (C(60)HyFn) have recently gained considerable attention as promising candidates for neurodegenerative states. We aimed to examine the effects on TRPM2 and TRPM7 gene expression of C(60)HyFn due to marked antioxidant activity in HHcy mice. METHODS C57BL/6 J. mice were divided into… CONTINUE READING