The effects of host immunity on virulence-transmissibility relationships in the rodent malaria parasite Plasmodium chabaudi.

Abstract

Here we examined the impact of host immunity on relationships between parasite virulence, transmission rate, intrinsic growth rate and host recovery rate in the rodent malaria parasite, Plasmodium chabaudi. Groups of naïve and immunized mice were infected with 1 of 10 cloned lines of parasites and their infection dynamics were monitored for 19 days. We… (More)

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