The effects of high‐intensity interval training on glucose regulation and insulin resistance: a meta‐analysis

  title={The effects of high‐intensity interval training on glucose regulation and insulin resistance: a meta‐analysis},
  author={Charlotte Jelleyman and Thomas Yates and Gary O'Donovan and L. J. Gray and James A. King and Kamlesh Khunti and M. J. Davies},
  journal={Obesity Reviews},
The aim of this meta-analysis was to quantify the effects of high-intensity interval training (HIIT) on markers of glucose regulation and insulin resistance compared with control conditions (CON) or continuous training (CT). [] Key Method Databases were searched for HIIT interventions based upon the inclusion criteria: training ≥2 weeks, adult participants and outcome measurements that included insulin resistance, fasting glucose, HbA1c or fasting insulin.
Aerobic Interval Training and Cardiometabolic Health in Patients with Type 2 Diabetes: A Meta-Analysis
In conclusion, despite a limited number of studies, INT improves cardiometabolic health especially for VO2max and HbA1c among patients with type 2 diabetes, and might be considered an alternative to MICT.
High‐intensity interval exercise versus moderate‐intensity continuous exercise on postprandial glucose and insulin responses: A systematic review and meta‐analysis
We performed a meta‐analysis to investigate the effects of high‐intensity interval exercise (HIIE) as compared to moderate‐intensity exercise (MIE) and a control condition (CON) on postprandial
Effectiveness of high-intensity interval training on glycemic control and cardiorespiratory fitness in patients with type 2 diabetes: a systematic review and meta-analysis
HIIT may induce more positive effects in cardiopulmonary fitness than MICT in T2D patients, and elicited a significant reduction in BMI, body fat, HbA1c, fasting insulin, and VO2peak in patients with type 2 diabetes.
The effect of different volumes of high-intensity interval training on proinsulin in participants with the metabolic syndrome: a randomised trial
Higher-volume HIIT (4HIIT) improved insulin quality in MetS participants without type 2 diabetes and reduced fasting intact proinsulin concentration indices from pre to post intervention.
A systematic review and meta‐analysis of interval training versus moderate‐intensity continuous training on body adiposity
HIIT/SIT appears to provide similar benefits to MICT for body fat reduction, although not necessarily in a more time‐efficient manner, however, neither short‐term HIIT/ SIT nor MICT produced clinically meaningful reductions in body fat.
Residual Impact of Concurrent, Resistance, and High-Intensity Interval Training on Fasting Measures of Glucose Metabolism in Women With Insulin Resistance
It is revealed that HIIT reduces FPG and RT reduces FI 24-h post-training; both exercise interventions alone have remarkably better residual effects on F PG and FI (post-72h) than CT in women with insulin resistance.
High intensity interval training plays an effective role in improvement of insulin resistance and reduction of serum FGF21 in obese subjects, which may be due to an improved F GF21 resistance.


The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women
HIIE three times per week for 15 weeks compared to the same frequency of SSE exercise was associated with significant reductions in total body fat, subcutaneous leg and trunk fat, and insulin resistance in young women.
Feasibility and preliminary efficacy of high intensity interval training in type 2 diabetes.
Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial
The results suggest that training with alternating intensity, and not just training volume and mean intensity, is a key determinant of changes in whole body glucose disposal in individuals with type 2 diabetes.
The effects of a 2 week modified high intensity interval training program on the homeostatic model of insulin resistance (HOMA-IR) in adults with type 2 diabetes.
Observations tend to support the positive health benefits of HITT for individuals with type 2 diabetes reported in recently published data, however, they suggest that the magnitude of the disease should be assessed when examining the effects of exercise interventions in individuals with T2D.
Interval training in men at risk for insulin resistance.
Eucaloric AER and INT appear to affect fasting glucose, OGTT and VO2max similarly, while INT may have a greater impact on HOMA-IR and zMS.
Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta‐analysis of controlled clinical trials
Exercise training reduces HbA(1c) by an amount that should decrease the risk of diabetic complications, but no significantly greater change in body mass was found when exercise groups were compared with control groups.
Reducing the Intensity and Volume of Interval Training Diminishes Cardiovascular Adaptation but Not Mitochondrial Biogenesis in Overweight/Obese Men
While improvements in aerobic capacity and exercise performance were different between groups, changes in oxidative capacity were similar despite reductions in both training intensity and volume.