The effects of herpes simplex virus type 1 on cellular DNA-dependent RNA polymerase activities.

An investigation of the activity of nuclear RNA polymerase following infection of LS cells with HSV-1 shows a decline in both major activities. This effect is not entirely due to inhibition of cellular protein synthesis, and the effect of alpha-amanitin-sensitive RNA polymerase is mediated by a protein(s) synthesized in the infected cell. Changes in the… CONTINUE READING



Citations per Year

208 Citations

Semantic Scholar estimates that this publication has 208 citations based on the available data.

See our FAQ for additional information.