The effects of hairpin loops on ligand-DNA interactions.

Abstract

Hairpin nucleic acids are frequently used in physical studies due to their greater thermal stability compared to their equivalent duplex structures. They are also good models for more complex loop-containing structures such as quadruplexes, i-motifs, cruciforms, and molecular beacons. Although a connecting loop can increase stability, there is little… (More)
DOI: 10.1021/jp904830m

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