The effects of gum arabic oral treatment on the metabolic profile of chronic renal failure patients under regular haemodialysis in Central Sudan

  title={The effects of gum arabic oral treatment on the metabolic profile of chronic renal failure patients under regular haemodialysis in Central Sudan},
  author={Adil Ahmed Ali and Khalid Eltom Ali and Abdelbagy Fadlalla and Khalid Eltahir Khalid},
  journal={Natural Product Research},
  pages={12 - 21}
This study aimed at assessing the effect of gum arabic (Acacia senegal) oral treatment on the metabolic profile of chronic renal failure (CRF) patients. A total of 36 CRF patients (under regular haemodialysis) and 10 normal subjects participated in this study. The patients were randomly allocated into three groups–group A: 12 CRF patients under low-protein diet (LPD) (<40 g day−1) and gum arabic (50 g day−1) treatment; group B: 14 CRF patients under LPD and gum arabic, iron (ferrous sulphate… 
Gum Arabic (Acacia Senegal) Augmented Total Antioxidant Capacity and Reduced C-Reactive Protein among Haemodialysis Patients in Phase II Trial
GA has revealed potent antioxidative and anti-inflammatory properties in haemodialysis patients and significantly augmented total antioxidant capacity level and attenuated oxidative stress and inflammatory markers among haemodermalysis patients.
The Effect of Gum Arabic in Treatment of Kidney Dysfunction in Chickens
The results obtained from this study suggested that oral administration of Gum Arabic extract may be helpful in the prevention of kidney dysfunction and may represent an effective therapy that normalizes serum creatinine and serum uric acid levels in chickens.
Protective Effects of Oral Gum Arabic Administration on Hyperlipidemia Experimentally Induced in Donkeys (Equusasinus asinus)
It is to be concluded that daily intake of gum Arabic at dose rate of 50g/day for seven successive days delayed the increase in triglycerides as well as cholesterol concentration, and hence induction of hyperlipemia, that considered to be of value in controlling hyperlipidemia in donkeys.
Effects of Gum Arabic in rats with adenine-induced chronic renal failure
Gum Arabic (GA [Acacia senegal]) is reputed, in Arabian medicinal practices, to be useful in treating patients with chronic renal failure (CRF), albeit without strong scientific evidence. We have
The effects of dietary supplementation with Gum arabicon blood pressure and renal function in subjects with Type 2diabetes mellitus
It is suggested that Gum arabic has beneficial effects on blood pressure but no immediate beneficial effect on renal function in either diabetic cohort.
Ameliorating effect of gum arabic and lemongrass on chronic kidney disease induced experimentally in rats
It is concluded that oral administration of GA or LG could conceivably alleviate adverse effects of CKD which might be ascribed to their antioxidant and free radical-scavenging properties.
Dietary Fibers (Gum Arabic) Supplementation Modulates Hepatic and Renal Profile Among Rheumatoid Arthritis Patients, Phase II Trial
Gum Arabic presents hepatic and renal protective effects among RA patients, evidenced by the significant reduction of urea and liver enzymes, and can be recommended as a dietary supplement for RA patients.
Effect of Gum Arabic on Oxidative Stress and Inflammation in Adenine–Induced Chronic Renal Failure in Rats
The mechanism of the reported salutary effect of GA in adenine‐induced CRF is associated with mitigation of the adenines‐induced inflammation and generation of free radicals.
Anemia in adenine‐induced chronic renal failure and the influence of treatment with gum acacia thereon (1063.4)
A general improvement in the renal status of rats with CRF after GA is shown due to its anti‐inflammatory and anti‐oxidant actions, and reduction of the uremic toxin IS, which is known to suppress Epo production, and this may be the basis of its ameliorative actions on the indices of anemia studied.
Bioactive of Gum Arabic ameliorated the oxidative damage and had increased the regenerative and reparative capacity of liver in mice through free radical scavenging properties and biochemical parameters were restored by Gum Arabic.


Supplementation with gum arabic fiber increases fecal nitrogen excretion and lowers serum urea nitrogen concentration in chronic renal failure patients consuming a low-protein diet.
Fecal bacterial mass and fecal nitrogen content were significantly increased during supplementation with gum arabic compared with the baseline LPD or supplementation with pectin, and serum urea nitrogen was significantly decreased.
Digestible fiber (gum arabic), nitrogen excretion and urea recycling in rats.
Abstract The effect of dietary fiber and level of amino acid (AA) intake on 1) partitioning of N excretion between urine and feces, 2) level of dietary AA on urea N kinetics, and 3) reutilization of
Fermentable fibers or oligosaccharides reduce urinary nitrogen excretion by increasing urea disposal in the rat cecum.
Results indicate that under these dietary conditions, the addition of oligosaccharides to the diet induced a 20 to 30% decrease in blood urea and renal and renal nitrogen excretion relative to the control, indicating a potential for oligOSaccharide diet therapy in chronic renal disease.
Evaluation of certain food additives and contaminants.
This report presents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives and contaminants, with a view to recommending acceptable daily
Specifications for gum arabic (Acacia senegal); analytical data for samples collected between 1904 and 1989.
The availability of well-preserved gum arabic samples, collected between 1904 and 1939, has enabled invaluable data to be added to those derived from samples from the most recent crops, and the resulting analytical data substantiate and greatly extend the quantitative information available previously for the chemical characterization of gumArabic for regulatory and trade purposes.
Evaluation of certain food additives and contaminants.
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