The effects of ginsenoside Rg1 on chronic stress induced depression-like behaviors, BDNF expression and the phosphorylation of PKA and CREB in rats.

@article{Liu2016TheEO,
  title={The effects of ginsenoside Rg1 on chronic stress induced depression-like behaviors, BDNF expression and the phosphorylation of PKA and CREB in rats.},
  author={Zhao Liu and Yihang Qi and Ziyi Cheng and Xiuzhi Zhu and Cuiqin Fan and Shu-Yan Yu},
  journal={Neuroscience},
  year={2016},
  volume={322},
  pages={358-69}
}
Depression is a common neuropsychiatric disorder which has been associated with a wide range of structural and functional changes within specific brain regions. Ginsenoside Rg1 has been shown to exert a number of neuroprotective effects as demonstrated in various in vivo and in vitro studies. However, little information is available regarding the site and mechanisms of ginsenoside Rg1 in promoting antidepressant effects. The present study aimed to investigate the neuroprotective and… CONTINUE READING