The effects of general anaesthetics on carbachol-evoked gamma oscillations in the rat hippocampus in vitro.

@article{Dickinson2003TheEO,
  title={The effects of general anaesthetics on carbachol-evoked gamma oscillations in the rat hippocampus in vitro.},
  author={Robert J. Dickinson and S Awaiz and Miles A. Whittington and William Robert Lieb and Nicholas P Franks},
  journal={Neuropharmacology},
  year={2003},
  volume={44 7},
  pages={864-72}
}
The effects of general anaesthetics and temperature on carbachol-evoked gamma oscillations in the rat hippocampal brain slice preparation were investigated. The frequency of the oscillations was found to be dependent on temperature in the range 32-25 degrees C, with a linear reduction in frequency from 40-17 Hz over this temperature range. The volatile anaesthetics isoflurane and halothane, and the intravenous anaesthetics thiopental, propofol and R(+)-etomidate caused a reduction in the… CONTINUE READING

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