The effects of fresh embryo transfers and elective frozen/thawed embryo transfers on pregancy outcomes in poor ovarian responders as defined by the Bologna criteria

@article{elik2015TheEO,
  title={The effects of fresh embryo transfers and elective frozen/thawed embryo transfers on pregancy outcomes in poor ovarian responders as defined by the Bologna criteria},
  author={Serdar Çelik and Niyazi Emre Turgut and Erbil Yağmur and Kubra Boynukalin and Dilek Cengiz Çelik and Necati Findikli and Sevim Purisa and Mustafa Bahçeci},
  journal={Turkish Journal of Obstetrics and Gynecology},
  year={2015},
  volume={12},
  pages={132 - 138}
}
Objective: To compare the effects of fresh embryo transfers (ET) and elective frozen/thawed embryo transfers (eFET) on implantation, clinical pregnancy, and live birth rates in poor ovarian responders, as defined by the Bologna criteria. Materials and Methods: All electronic databases of embryo transfers between January 2011 and January 2014 were retrospectively reviewed. Two hundred fifty-nine of all the fresh ET and 96 of all eFET were included into the study. An antagonist protocol with… 

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The clinical outcomes of fresh versus frozen embryos transfer in women ≥40 years with poor ovarian response
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FET after the freeze-all strategy had no beneficial impact on the clinical outcomes of women ≥40 years with POR and the clinical pregnancy and miscarriage rates, and neonatal characteristics were similar between the 2 groups.
Impact of elective frozen vs. fresh embryo transfer strategies on cumulative live birth: Do deleterious effects still exist in normal & hyper responders?
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Compared with a fresh-transfer strategy, the e-FET strategy resulted in a higher CLBR among patients with >10 oocytes retrieved during stimulated cycles, and birth weights were significantly lower for fresh ET, 3064 versus 3201 g for singletons (p<0.001) and perinatal and obstetrical outcomes were nonsignificantly different between fresh and e- FET arms.
Fresh versus frozen embryo transfer in women with thin endometrium: a retrospective cohort study.
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For women with a thin endometrium who were undergoing IVF, the live birth rate, clinical pregnancy rate, and biochemical pregnancy rate after frozen ET were significantly higher than in the fresh ET group.
Comparison of a “freeze-all” strategy versus a “fresh transfer” strategy among poor responders in Assisted Reproductive Technology (ART)—An observational study
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Success of IVF treatment can be improved in poor responder by implementing “freeze all” policy, and the proportional comparison among the two groups was found to be statistically significant, showing a higher CPR in the FET group.
Accumulation of embryos over 3 natural modified IVF (ICSI) cycles followed by transfer to improve the outcome of poor responders
TLDR
Accumulation of embryos through 3 NM-IVF cycles before transfer improves livebirth rates and reduces the risk of lacking an embryo for transfer in poor responders aged ≥35 years.
COMPARISON OF A 'FREEZE-ALL' STRATEGY VERSUS A 'FRESH TRANSFER' STRATEGY AMONG POOR RESPONDERS IN ASSISTED REPRODUCTIVE TECHNOLOGY (ART)
TLDR
In poor responder group of patients, IVF outcomes can be improved by implementing freeze all policy, which could be achieved with the help of Pre implantation genetic screening synchronized with latest endometrium receptivity markers.
Does freeze-all policy affect IVF outcomes in poor responders ? Short Title : Freeze all policy in POR
TLDR
In this study, the freeze-all strategy had no impact on IVF outcomes among poor responders according to the Bologna criteria and a multi-centric study including a large number of patients was performed.
A universal freeze all strategy: why it is not warranted
  • B. AtaE. Seli
  • Medicine
    Current opinion in obstetrics & gynecology
  • 2017
TLDR
EFET seems to have limited potential to improve effectiveness of assisted reproductive technology, which could be limited to hyper-responders, and switching to a universal eFET strategy does not seem justified.
...
...

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