The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia.

@article{Drake1999TheEO,
  title={The effects of finasteride on scalp skin and serum androgen levels in men with androgenetic alopecia.},
  author={Lynn A. Drake and Maria K. Hordinsky and Volker Fiedler and James M. Swinehart and Walter P. Unger and P C Cotterill and Diane M. Thiboutot and N. Lowe and Charles Andrew Jacobson and David E.G. Whiting and Sven Stieglitz and Stephen J. Kraus and Eur Ing John Griffin and Dana Vedder Weiss and Patrick Carrington and C Gencheff and G. William Cole and David M. Pariser and Edwin S Epstein and Wesley Tanaka and Aimee L Dallob and Kristel Vandormael and Laura M. Geissler and Joanne Waldstreicher},
  journal={Journal of the American Academy of Dermatology},
  year={1999},
  volume={41 4},
  pages={
          550-4
        }
}
BACKGROUND Data suggest that androgenetic alopecia is a process dependent on dihydrotestosterone (DHT) and type 2 5alpha-reductase. Finasteride is a type 2 5alpha-reductase inhibitor that has been shown to slow further hair loss and improve hair growth in men with androgenetic alopecia. OBJECTIVE We attempted to determine the effect of finasteride on scalp skin and serum androgens. METHODS Men with androgenetic alopecia (N = 249) underwent scalp biopsies before and after receiving 0.01, 0… CONTINUE READING
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