The effects of exercise and stress on the survival and maturation of adult-generated granule cells.

@article{Snyder2009TheEO,
  title={The effects of exercise and stress on the survival and maturation of adult-generated granule cells.},
  author={Jason Scott Snyder and Lucas R. Glover and Kaitlin M Sanzone and J Frances Kamhi and Heather A. Cameron},
  journal={Hippocampus},
  year={2009},
  volume={19 10},
  pages={898-906}
}
Stress strongly inhibits proliferation of granule cell precursors in the adult dentate gyrus, whereas voluntary running has the opposite effect. Few studies, however, have examined the possible effects of these environmental manipulations on the maturation and survival of young granule cells. We examined the number of surviving granule cells and the proportion of young neurons that were functionally mature, as defined by seizure-induced immediate-early gene (IEG) expression, in 14- and 21-day… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 78 extracted citations

How the Body Talks

View 5 Excerpts
Highly Influenced

Differential effects of stress and glucocorticoids on adult neurogenesis.

Current topics in behavioral neurosciences • 2013
View 9 Excerpts
Highly Influenced

Stress, stress hormones, and adult neurogenesis.

Experimental neurology • 2012
View 8 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 65 references

Neuronal differentiation in the adult hippocampus recapitulates embryonic development.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2005
View 4 Excerpts
Highly Influenced

Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2001
View 4 Excerpts
Highly Influenced

IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress.

Proceedings of the National Academy of Sciences of the United States of America • 2008

Similar Papers

Loading similar papers…