The effects of dynamic loading on the intervertebral disc

Abstract

Loading is important to maintain the balance of matrix turnover in the intervertebral disc (IVD). Daily cyclic diurnal assists in the transport of large soluble factors across the IVD and its surrounding circulation and applies direct and indirect stimulus to disc cells. Acute mechanical injury and accumulated overloading, however, could induce disc… (More)
DOI: 10.1007/s00586-011-1827-1

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