The effects of dynamic axial loading on the rat growth plate.

  title={The effects of dynamic axial loading on the rat growth plate.},
  author={Naoko Ohashi and Alexander G. Robling and David B. Burr and C. H. Turner},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  volume={17 2},
Longitudinal bone growth can be suppressed by compressive loading. In this study, we applied three different magnitudes (17, 8.5, and 4N) of compressive force to growing rat ulnas 10 minutes/day for 8 days and investigated the effects on the distal growth plate biology. Further, to investigate growth rate recovery after cessation of loading, we examined rats 7 days after the loading period. Longitudinal growth of the ulna was suppressed in a dose-dependent manner by applied compressive force… CONTINUE READING


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