The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response.

@article{Zarrindast2010TheEO,
  title={The effects of dopaminergic drugs in the ventral hippocampus of rats in the nicotine-induced anxiogenic-like response.},
  author={Mohammad Reza Zarrindast and Nima Naghdi-Sedeh and Mohammad Mahdi Nasehi and Hedayat Sahraei and Farideh Bahrami and Fereshteh Asadi},
  journal={Neuroscience letters},
  year={2010},
  volume={475 3},
  pages={156-60}
}
Nicotine an active alkaloid of tobacco has dopaminergic properties. The drug alters anxiety-like behavior in rodents. Ventral hippocampus (VHC) may be a site for modulation of anxiety-like behaviors. The possible involvement of ventral hippocampal dopaminergic receptor mechanism in the nicotine influence on anxiogenic-like response has been investigated in the present study. The effects of apomorphine, sulpiride and SCH23390 on nicotine response in elevated plus maze in rats have been… CONTINUE READING