The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. I. Morphological characteristics.

@article{Fricker1997TheEO,
  title={The effects of donor stage on the survival and function of embryonic striatal grafts in the adult rat brain. I. Morphological characteristics.},
  author={R A Fricker and Eduardo M. Torres and Stephen B. Dunnett},
  journal={Neuroscience},
  year={1997},
  volume={79 3},
  pages={695-710}
}
The effects of the stage of donor embryos on the survival of grafts from different neuronal cell types have been well documented. Indeed, this parameter has been shown to be highly important in the survival and function of transplants of various tissues of the CNS. However this question has not been addressed in grafts of embryonic striatal tissue transplanted into animal models of Huntington's disease. In this study, rats which had received a unilateral ibotenic acid lesion in the dorsal… CONTINUE READING
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