The effects of diuresis on the pharmacokinetics of the loop diuretics furosemide and torsemide in patients with heart failure.

@article{Gottlieb1998TheEO,
  title={The effects of diuresis on the pharmacokinetics of the loop diuretics furosemide and torsemide in patients with heart failure.},
  author={Stephen S Gottlieb and Meenakshi Khatta and Deborah Wentworth and David S Roffman and Michael L. Fisher and William G. Kramer},
  journal={The American journal of medicine},
  year={1998},
  volume={104 6},
  pages={533-8}
}
PURPOSE To evaluate the pharmacokinetics of furosemide and torsemide before and after diuresis in patients presenting with marked fluid overload. SUBJECTS AND METHODS We studied 44 patients with New York Heart Association class III or IV heart failure, ejection fraction < or =40%, and an estimated excess fluid body weight > or =6.8 kg. Oral furosemide or… CONTINUE READING