The effects of dexmedetomidine dosage on cerebral vasospasm in a rat subarachnoid haemorrhage model.


We investigated the effect of two different doses of dexmedetomidine on vasospasm in a rat model of subarachnoid haemorrhage (SAH). SAH was induced by injecting 0.3 mL blood into the cisterna magna in all rat groups except the control (Group C). At 1 hour and 24 hours after SAH, 5 microg/kg dexmedetomidine was given to group D5, and 10 microg/kg… (More)
DOI: 10.1016/j.jocn.2009.10.012


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