The effects of dexamethasone on bone fusion in an experimental model of posterolateral lumbar spinal arthrodesis.

@article{Sawin2001TheEO,
  title={The effects of dexamethasone on bone fusion in an experimental model of posterolateral lumbar spinal arthrodesis.},
  author={Paul D Sawin and Curtis A. Dickman and Neil R. Crawford and Matthew S. Melton and William D Bichard and Volker K. H. Sonntag},
  journal={Journal of neurosurgery},
  year={2001},
  volume={94 1 Suppl},
  pages={76-81}
}
OBJECT The use of corticosteroid agents during the healing phase after spinal arthrodesis remains controversial. Although anecdotal opinion suggests that corticosteroids may inhibit bone fusion, such an effect has not been substantiated in clinical trials or laboratory investigations. This study was undertaken to delineate the effect of exogenous corticosteroid administration on bone graft incorporation in an experimental model of posterolateral lumbar fusion. METHODS An established, well… CONTINUE READING

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