The effects of deleterious mutations on linked, neutral variation in small populations.

Abstract

The effects of recessive, deleterious mutations on genetic variation at linked neutral loci can be heterozygosity-decreasing because of reduced effective population sizes or heterozygosity-increasing because of associative overdominance. Here we examine the balance between these effects by simulating individual diploid genotypes in small panmictic… (More)

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@article{Plsson1999TheEO, title={The effects of deleterious mutations on linked, neutral variation in small populations.}, author={Snaebj{\"{o}rn P{\'a}lsson and Pekka Pamilo}, journal={Genetics}, year={1999}, volume={153 1}, pages={475-83} }