The effects of cocaine on regional brain glucose metabolism is attenuated in dopamine transporter knockout mice.


Cocaine's ability to block the dopamine transporter (DAT) is crucial for its reinforcing effects. However the brain functional consequences of DAT blockade by cocaine are less clear since they are confounded by its concomitant blockade of norepinephrineand serotonin transporters. To separate the dopaminergic from the non-dopaminergic effects of cocaine on… (More)
DOI: 10.1002/syn.20503


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