The effects of cimetidine and ranitidine on the pharmacokinetics of cifenline.

Abstract

Twelve healthy subjects completed an open single dose study to evaluate the effect of co-administration of cimetidine and ranitidine on the pharmacokinetics of cifenline. Each subject received a single 160 mg dose of cifenline alone, in combination with cimetidine (300 mg four times daily), and with ranitidine (150 mg twice daily). The H2-receptor… (More)

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@article{Massarella1991TheEO, title={The effects of cimetidine and ranitidine on the pharmacokinetics of cifenline.}, author={Joseph Massarella and Tullia Maria Defeo and Johella Liguori and Sharon Passe and K Aogaichi}, journal={British journal of clinical pharmacology}, year={1991}, volume={31 4}, pages={481-3} }