The effects of ciliary neurotrophic factor on neurological function and glial activity following contusive spinal cord injury in the rats

@article{Ye2004TheEO,
  title={The effects of ciliary neurotrophic factor on neurological function and glial activity following contusive spinal cord injury in the rats},
  author={Junli Ye and Li Qiong Cao and Ruiyao Cui and Aijun Huang and Cheng He},
  journal={Brain Research},
  year={2004},
  volume={997},
  pages={30-39}
}
Ciliary neurotrophic factor (CNTF) has been implicated in the pathophysiology of injury to the central nervous system. The rapid increase in CNTF production following spinal cord injury (SCI) in rats is thought to serve a role in the neuronal survival and functional recovery. In this study, 40 SD rats were divided into four groups: sham-operated group, saline-treated group, 5- and 10-microg CNTF group. Saline and CNTF were given through lumbar intrathecal catheter for 10 days after T10 segment… CONTINUE READING
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