The effects of cholecystokinin on parietal cell secretion in isolated gastric glands.

@article{Zdon1985TheEO,
  title={The effects of cholecystokinin on parietal cell secretion in isolated gastric glands.},
  author={Michael J. Zdon and GarthH. Ballantyne and David Eugene Schafer and Gary R. Fratesi and Jenny R. Roberts and M Tishkoff and Irvin. M. Modlin},
  journal={Surgery},
  year={1985},
  volume={98 6},
  pages={
          1038-44
        }
}
Cholecystokinin (CCK), a peptide hormone found in both gut and brain, shares amino acid homologies with gastrin and has previously been shown to stimulate gastric acid secretion in whole animal experiments. To investigate possible direct effects of CCK apart from extrinsic neural and hormonal influences, we have investigated the effects of the sulfated octapeptide of CCK (CCK-8) in rabbit isolated gastric glands using 14C-aminopyrine accumulation and intrinsic factor (IF) secretion as markers… CONTINUE READING