The effects of changes in muscle length during diastole on the calcium transient in ferret ventricular muscle.

@article{Allen1988TheEO,
  title={The effects of changes in muscle length during diastole on the calcium transient in ferret ventricular muscle.},
  author={David G. Allen and Colin G. Nichols and Godfrey L. Smith},
  journal={The Journal of physiology},
  year={1988},
  volume={406},
  pages={359-70}
}
1. Ferret papillary muscles were isolated and injected with aequorin to measure intracellular Ca2+ concentration [( Ca2+]i). Developed tension and [Ca2+]i were measured in response to length changes. 2. A maintained reduction in muscle length produced an immediate decrease in developed tension followed by slow decline over 10-20 min. This slow decline in tension was accompanied by a slow decline in the amplitude of the systolic [Ca2+]i rise (the Ca2+ transient). The immediate decrease in… CONTINUE READING

From This Paper

Topics from this paper.
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…