The effects of certain H(1)-antagonists on visual evoked potential in rats.

@article{Iwamura2003TheEO,
  title={The effects of certain H(1)-antagonists on visual evoked potential in rats.},
  author={Yoshihiro Iwamura and Yoko Fujii and Chiaki Kamei},
  journal={Brain research bulletin},
  year={2003},
  volume={61 4},
  pages={393-8}
}
The present study was undertaken to clarify the effects of certain H(1)-antagonists on visual evoked potential (VEP) in rats. Pyrilamine (5 and 10 mg/kg), diphenhydramine (5 and 10 mg/kg) and chlorpheniramine (10 and 20 mg/kg) caused a significant reduction in the amplitude of late VEP components (P(3)-N(3), N(3)-P(4)), although these drugs showed no significant changes in early VEP components (P(1)-N(1), N(1)-P(2)). Cyproheptadine caused a slight enhancement of late components of VEP at a dose… CONTINUE READING
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