The effects of calorie restriction on operant-responding for alcohol in the alcohol preferring (iP) rat

@article{Guccione2012TheEO,
  title={The effects of calorie restriction on operant-responding for alcohol in the alcohol preferring (iP) rat},
  author={Lisa Guccione and Antonio Paolini and Jim Penman and Elvan Djouma},
  journal={Behavioural Brain Research},
  year={2012},
  volume={230},
  pages={281-287}
}
Calorie restriction (CR) is well established in the research literature to have several beneficial effects on health and has also been found to induce anxiolytic effects in the rat. Heightened levels of stress and anxiety are often regarded as key precipitating factors of relapse to substance abuse and alcohol addiction. In this study, the potential implication of a 25% CR diet in altering drug-seeking and relapse like behaviour through its capacity to influence anxiolytic-like behavioural… CONTINUE READING
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