The effects of body weight status on orthostatic intolerance and predisposition to noncardiac syncope

@article{Christou2017TheEO,
  title={The effects of body weight status on orthostatic intolerance and predisposition to noncardiac syncope},
  author={Georgios A Christou and Dimitrios N. Kiortsis},
  journal={Obesity Reviews},
  year={2017},
  volume={18},
  pages={370 - 379}
}
Orthostatic intolerance (OI) is frequently the mechanism underlying the occurrence of noncardiac syncope (NCS) and is associated with substantial risk for injury. Body weight status appears to be a modifier of orthostatic responses and possibly influences the propensity to NCS. The majority of cross‐sectional studies have found that the lower the body mass index (BMI) the greater the predisposition to OI is, accompanied with both down‐regulation of sympathetic nervous system activity and up… 

Gastrocnemius Muscle Contraction and Its Role in Orthostatic Anti-Gravity Adjustment – The Effects of Body Mass Index

The study showed that BMI affects predominantly the initial values of GM parameters at rest and MAPF without influence on its antigravity contractility associated with active straightening.

Pathophysiology of Noncardiac Syncope in Athletes

Postexercise NCS appears to result from hypotension due to impaired postexercise vasoconstriction, as well as from hypocapnia, and athletes have been shown to exhibit differential orthostatic responses compared with nonathletes, involving augmented stroke volume and increased peripheral vasodilation in the former, with possibly lower propensity to Orthostatic intolerance.

Body mass index is a promising predictor of response to oral rehydration saline in children with vasovagal syncope

Abstract Background: Vasovagal syncope (VVS) greatly impairs quality of life. The therapeutic efficacy of oral rehydration saline (ORS) for unselected VVS patients is not satisfactory due to the

Similar Cerebral Blood Flow and Autonomic Responses to Upright Tilt Test in Adult Patients With Different Hemodynamic Mechanisms Leading to Reflex Syncope.

Although different cardiovascular hemodynamic mechanisms of reflex syncope exist in adult patients, cerebrovascular hypoperfusion and autonomic modulation occur to a similar extent.

Orthostatic intolerance after bariatric surgery: A systematic review and meta‐analysis

A systematic review using PubMed, Scopus, CINAHL, Cochrane Database of Systematic Reviews and the Cochrane Central Register of Controlled Trials to identify relevant articles found one study reporting the 5‐years cumulative incidence of orthostatic intolerance post‐bariatric surgeries as only 4.2%.

Risk factors and psychological impact of syncope in migraine patients

The potential roles of vascular risk factors in the association between migraine and syncope were showed and the debilitating psychological impact of co-morbid syncope in migraine patients warrants clinical attention of treating physicians.

Body mass index is decreased in children and adolescents with postural tachycardia syndrome.

The intent was to explore the predictive value of body mass index (BMI) in differentiating between vasovagal syncope (VVS) and postural tachycardia syndrome (POTS) in children and adolescents.

Impact of body mass index on left atrial dimension in HOCM patients

BMI was independently associated with LA diameter; however, it was not an independent predictor of prevalence of AF, suggesting that BMI may promote incidence of AF through LA enlargement in HOCM.

Syncope risk factors among military training soldiers; A case-control study

Lower BMI, positive history of syncope, smoking, depression, and stress were significant risk factors ofsyncope occurrence among training soldiers and higher BMI has protective role in syncope occurrence.

Early detection of the risk for orthostatic hypotension among the elderly people

The main precipitating factors included a long time for a shower, prolonged bed rest, heavy carbohydrate meals, obesity, hypertension, diabetes mellitus, cardiac diseases, and anemia and approximately one-fifth of the clients suffered from orthostatic hypotension.

References

SHOWING 1-10 OF 101 REFERENCES

Severe orthostatic hypotension following weight reduction surgery.

Although losing weight is a known treatment option for hypertension, exaggerated reversal of obesity-related hypertension might result in orthostatic hypotension, and it is believed that rapid weight loss may impair sympathetic function and blood pressure control.

Long-Term Sympathoinhibitory Effects of Surgically Induced Weight Loss in Severe Obese Patients

Evidence is provided that massive weight loss induced by sleeve gastrectomy triggers profound sympathoinhibitory effects, associated with a stable and significant reduction in plasma leptin levels, whereas the improvement in insulin sensitivity was attenuated with time and unrelated to the sympathoinhibition.

Pathophysiological mechanisms of noncardiac syncope in athletes.

Sympathetic Neural Adaptation to Hypocaloric Diet With or Without Exercise Training in Obese Metabolic Syndrome Subjects

The addition of moderate-intensity aerobic exercise training to a weight loss program does not confer additional benefits on resting SNS activity, suggesting that weight loss is the prime mover in sympathetic neural adaptation to a hypocaloric diet.

Orthostatic hypotension in the healthy elderly.

Effects of dietary weight loss on sympathetic activity and cardiac risk factors associated with the metabolic syndrome.

Weight loss by a hypocaloric diet with moderate sodium restriction diminishes SNS activity in MetS subjects, which may be due to the consequences of decreased leptin concentration, enhanced insulin sensitivity, or improvements in cardiac baroreflex function.

The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components.

Divergent effects of successful weight loss maintenance on whole-body norepinephrine spillover rate and MSNA suggest organ-specific differentiation in SNS adaptation to weight loss under conditions of negative vs. stable energy balance.

Factors associated with orthostatic hypotension in the Chinese population in Taiwan.

Reduced heart rate variability correlates with insulin resistance but not with measures of obesity in population undergoing laparoscopic Roux-en-Y gastric bypass.

...