The effects of berberine on the pharmacokinetics of cyclosporin A in healthy volunteers.

@article{Xin2006TheEO,
  title={The effects of berberine on the pharmacokinetics of cyclosporin A in healthy volunteers.},
  author={H-W Xin and X-C Wu and Qiguang Li and A-R Yu and M-Y Zhong and Y-Y Liu},
  journal={Methods and findings in experimental and clinical pharmacology},
  year={2006},
  volume={28 1},
  pages={
          25-9
        }
}
The effects of berberine (BBR) on the pharmacokinetics of ciclosporin A (CsA) were examined in healthy volunteers. Six healthy male volunteers were orally treated with 0.3 g BBR, twice daily for 10 days. Pharmacokinetic investigations on CsA at 6 mg/kg were done both before and at the end of the BBR treatment period. Another six healthy male volunteers were involved in the pharmacokinetic study with 3 mg CsA/kg, in which the subjects orally received the second single dose of 3 mg CsA/kg… CONTINUE READING

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