The effects of atropine and secoverine on gastric secretion and motility in the mouse isolated stomach

@article{Davison1983TheEO,
  title={The effects of atropine and secoverine on gastric secretion and motility in the mouse isolated stomach},
  author={J. Davison and B. Greenwood and A. Najafi-Farashah and N. Read},
  journal={British Journal of Pharmacology},
  year={1983},
  volume={79}
}
1 The isolated perfused stomach of the mouse was used to study the effect of atropine and secoverine on bethanechol‐induced gastric acid secretion and gastric motility. 2 Both atropine and secoverine inhibited cholinergically induced gastric acid secretion and gastric motility. 3 Inhibition of gastric acid secretion by atropine and secoverine occurred at a similar dose‐range (10−9 and 2 × 10−9m). 4 Secoverine inhibited bethanechol‐induced hypermotility at doses (10−11 m and above) that were… Expand

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