The effects of antidepressant drugs on salivary flow and content of sodium and potassium ions in human parotid saliva.

@article{Hunter1995TheEO,
  title={The effects of antidepressant drugs on salivary flow and content of sodium and potassium ions in human parotid saliva.},
  author={Kevin D. Hunter and WyndhamH. Wilson},
  journal={Archives of oral biology},
  year={1995},
  volume={40 11},
  pages={983-9}
}
Stimulated parotid saliva was collected, using the Carlson-Crittenden cup, from normal controls and patients on antidepressant drugs. The saliva from patients using amitriptyline, dothiepin (tricyclics), fluoxetine and paroxetine (selective serotonin re-uptake inhibitors; SSRI) was analysed for flow rate, [Na+] and [K+], and was compared with that from unmedicated, non-depressed volunteers for all variables. The tricyclic antidepressants produced a significant reduction in flow (amitriptyline… CONTINUE READING

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