The effects of antibiotics combined with natural polyphenols against clinical methicillin-resistant Staphylococcus aureus (MRSA).

@article{Lin2008TheEO,
  title={The effects of antibiotics combined with natural polyphenols against clinical methicillin-resistant Staphylococcus aureus (MRSA).},
  author={R. Lin and Yi-Ping Chin and W. Hou and Mei-Hsien Lee},
  journal={Planta medica},
  year={2008},
  volume={74 8},
  pages={
          840-6
        }
}
Novel therapies are needed to address the public health problem posed by methicillin-resistant STAPHYLOCOCCUS AUREUS (MRSA). In this study, we determined the effects of combinations of antibiotics and plant polyphenols against 20 clinical isolates of MRSA. The IN VITRO activities of 10 antibiotics and 15 natural polyphenols against the isolates were evaluated by determining minimum inhibitory concentrations (MICs). All isolates were susceptible to vancomycin and resistant to rifampicin, while… Expand
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References

SHOWING 1-10 OF 24 REFERENCES
Effect of certain bioactive plant extracts on clinical isolates of β‐lactamase producing methicillin resistant Staphylococcus aureus
Ethanolic extracts and some fractions from 10 Indian medicinal plants, known for antibacterial activity, were investigated for their ability to inhibit clinical isolates of β‐lactamase producingExpand
Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus.
TLDR
Aloe-emodin, an anthraquinone, and several licorice flavonoids showed potent antibacterial effects against MRSA, and theasinensin A, a polyphenol formed from (-)-epigallocatechin gallate, and polymeric proanthocyanidins obtained from fruits of Zizyphus jujuba var. Expand
Correlation between the activity of different fluoroquinolones and the presence of mechanisms of quinolone resistance in epidemiologically related and unrelated strains of methicillin-susceptible and -resistant Staphylococcus aureus.
TLDR
Trovafloxacin was the most active quinolone tested against S. aureus strains, followed by levofloxAcin and sparfloxacIn, whereas ciprofloxACin and norfloxacsin were the least activeQuinolones, in both the presence and absence of reserpine. Expand
Antibacterial activity of flavonoids against methicillin-resistant Staphylococcus aureus strains.
TLDR
It is concluded that the flavonoids chalcone, 2'(OH)-chal cone, 2',4'( OH)(2)-chalcone and 2,4(OH)(2-chalcone) might constitute promising therapeutic agents against infections with methicillin-resistant S. aureus strains. Expand
In Vitro Combined Effects of Cefozopran/Teicoplanin and Cefozopran/Vancomycin on Methicillin-Resistant Staphylococcus aureus
TLDR
The results suggest that treatment using TEIC or VCM with CZOP may be useful in treating MRSA infections, including polymicrobial infections and those involving Gram-negative rods. Expand
Antibiotics currently used in the treatment of infections caused by Staphylococcus aureus
TLDR
Most community-acquired strains of MRSA in Australia and New Zealand are non multiresistant (nmMRSA), and lincosamides (clindamycin, lincomycin or cotrimoxazole are the antibiotics of choice for less serious nmMRSA infections such as skin and soft tissue infections. Expand
Linezolid: a pharmacoeconomic review of its use in serious Gram-positive infections.
TLDR
Modelled analyses from the US indicate that, compared with vancomycin, linezolid is associated with lower total hospitalisation costs for the treatment of patients with cellulitis and has a favourable incremental cost-effectiveness ratio of approximately US30,000 dollars per QALY gained for patients with ventilator-associated pneumonia. Expand
Beta-Lactam Resistance: Clinical Implications for Pediatric Patients
  • A. Dajani
  • Medicine
  • The Journal of international medical research
  • 2002
TLDR
The challenge is to control the emergence of beta-lactamase-mediated resistance by using beta-Lactams judiciously, and the beta- lactam/beta-lacticamase inhibitor combinations have an important role to play in extending the usefulness of established beta- Lactam agents. Expand
Activity of plant flavonoids against antibiotic‐resistant bacteria
TLDR
Thirty eight plant‐derived flavonoids representing seven different structural groups were tested for activities against antibiotic‐resistant bacteria using the disc‐diffusion assay and broth dilution assay and the results of the radiolabel incorporation assay showed that myricetin inhibited protein synthesis by B. cepacia. Expand
Comparative Efficacy of Topical Moxifloxacin Versus Ciprofloxacin and Vancomycin in the Treatment of P. aeruginosa and Ciprofloxacin-Resistant MRSA Keratitis in Rabbits
TLDR
There is a potential value for topical moxifloxacin as a broad-spectrum agent in the treatment of bacterial keratitis, and vancomycin showed a trend toward statistical significance in performing better than control in treating ciprofloxacIn-resistant MRSA ker atitis in rabbits. Expand
...
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