The effects of amiloride and ouabain on urinary acidification by turtle bladder.

Abstract

To investigate the mechanism by which amiloride inhibits urinary acidification, its effects on H+ secretion were examined in the isolated urinary bladder of the fresh water turtle. In short-circuited turtle bladders amiloride inhibited H+ secretion by 30% and Na+ transport by 100%. Maximal inhibition was reached at 10(-4) M amiloride for both transport… (More)

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@article{Husted1979TheEO, title={The effects of amiloride and ouabain on urinary acidification by turtle bladder.}, author={Russell F. Husted and Patrick Rh Steinmetz}, journal={The Journal of pharmacology and experimental therapeutics}, year={1979}, volume={210 2}, pages={264-8} }