The effects of aging and dorsal hippocampal lesions: performance on spatial and nonspatial comparable versions of the water maze.

@article{Stoelzel2002TheEO,
  title={The effects of aging and dorsal hippocampal lesions: performance on spatial and nonspatial comparable versions of the water maze.},
  author={Carl R Stoelzel and Amy Jo Stavnezer and Victor H. Denenberg and Mattison Ward and Etan J. Markus},
  journal={Neurobiology of learning and memory},
  year={2002},
  volume={78 2},
  pages={217-33}
}
Aged intact and young hippocampal-lesioned rats show similar deficits on the spatial water maze. However, this does not necessitate that the source of these deficits in the aged animals is due to hippocampal damage. These water maze deficits may arise from other aging factors such as changes in thermoregulation, muscle fatigue, swim ability, and response to stress. Consequently, it is imperative to examine the performance of aged rats on a comparable nonhippocampal version of this task. Past… CONTINUE READING

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