The effects of aerobic exercise training at two different intensities in obesity and type 2 diabetes: implications for oxidative stress, low-grade inflammation and nitric oxide production

@article{Krause2013TheEO,
  title={The effects of aerobic exercise training at two different intensities in obesity and type 2 diabetes: implications for oxidative stress, low-grade inflammation and nitric oxide production},
  author={Maur{\'i}cio da Silva Krause and Josianne Rodrigues-Krause and Ciara O’Hagan and Paul Medlow and Gareth Davison and Davide Susta and Colin A G Boreham and Philip Newsholme and Mark Edward O’Donnell and Colin Murphy and Giuseppe De Vito},
  journal={European Journal of Applied Physiology},
  year={2013},
  volume={114},
  pages={251-260}
}
To investigate the effect of 16 weeks of aerobic training performed at two different intensities on nitric oxide (tNOx) availability and iNOS/nNOS expression, oxidative stress (OS) and inflammation in obese humans with or without type 2 diabetes mellitus (T2DM). Twenty-five sedentary, obese (BMI > 30 kg/m2) males (52.8 ± 7.2 years); 12 controls versus 13 T2DM were randomly allocated to four groups that exercised for 30 min, three times per week either at low (Fat-Max; 30–40 % VO2max) or… CONTINUE READING